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Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease: A Randomized Clinical Trial.

JAMA· 2023-04-04· rct

Sung-Jin Hong, Yong-Joon Lee, Seung-Jun Lee, Bum-Kee Hong, Woong Chol Kang, Jong-Young Lee, Jin-Bae Lee, Tae-Hyun Yang, Junghan Yoon, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong, Unknown

Stage: unknownIntegrity: okDOI: 10.1001/jama.2023.2487PMID: 36877807PMCID: PMC9989958

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Study design

rct

Verified findings

  • numeric_findings[0]

    {"unit":null,"label":"reported_value","value_text":"50"}

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    • CONCLUSIONS_AND_RELEVANCE · CONCLUSIONS_AND_RELEVANCE:S001

  • numeric_findings[1]

    {"unit":null,"label":"reported_value","value_text":"12"}

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    • DESIGN_SETTING_AND_PARTICIPANTS · DESIGN_SETTING_AND_PARTICIPANTS:S001

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    {"unit":null,"label":"reported_value","value_text":"50"}

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    • IMPORTANCE · IMPORTANCE:S001

  • numeric_findings[3]

    {"unit":null,"label":"reported_value","value_text":"50"}

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    • INTERVENTIONS · INTERVENTIONS:S001

  • numeric_findings[4]

    {"unit":null,"label":"reported_value","value_text":"3"}

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    • MAIN_OUTCOMES_AND_MEASURES · MAIN_OUTCOMES_AND_MEASURES:S001

  • population

    {"description":"Among patients with coronary artery disease, a treat-to-target LDL-C strategy of 50 to 70 mg/dL as the goal was noninferior to a high-intensity statin therapy for the 3-year composite of death, myocar","sample_size":null,"exclusion_summary":null,"inclusion_summary":null}

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    • CONCLUSIONS_AND_RELEVANCE · CONCLUSIONS_AND_RELEVANCE:S001

Limitations & not reported

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  • extension.rct_extension.allocation_ratio
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  • extension.rct_extension.itt_or_per_protocol
  • extension.rct_extension.primary_endpoint
  • extension.rct_extension.randomization_method
  • extension.rct_extension.sample_size_arms
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  • limitations
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